tailieunhanh - Báo cáo y học: "Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequencing and by microbiological culture"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequencing and by microbiological culture. | Available online http content 9 3 R46 Research article Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequencing and by microbiological culture Kate E Dempsey1 Marcello P Riggio1 Alan Lennon1 Victoria E Hannah1 Gordon Ramage1 David Allan2 and Jeremy Bagg1 Infection and Immunity Research Group Level 9 Glasgow Dental Hospital School 378 Sauchiehall Street Glasgow G2 3JZ UK 2The Queen Elizabeth National Spinal Injuries Unit Scotland South Glasgow University Hospitals Division Southern General Hospital 1345 Govan Road Glasgow G51 4TF UK Corresponding author Marcello P Riggio Received 28 Nov 2006 Accepted 14 May 2007 Published 14 May 2007 Arthritis Research Therapy 2007 9 R46 doi ar2201 This article is online at http content 9 3 R46 2007 Dempsey et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract It has been postulated that bacteria attached to the surface of prosthetic hip joints can cause localised inflammation resulting in failure of the replacement joint. However diagnosis of infection is difficult with traditional microbiological culture methods and evidence exists that highly fastidious or non-cultivable organisms have a role in implant infections. The purpose of this study was to use culture and cultureindependent methods to detect the bacteria present on the surface of prosthetic hip joints removed during revision arthroplasties. Ten consecutive revisions were performed by two surgeons which were all clinically and radiologically loose. Five of the hip replacement revision surgeries were performed because of