tailieunhanh - Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life. | Available online http content 10 1 R27 Research article High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life Fahad S Hanna1 2 3 4 Robin J Bell1 2 Flavia M Cicuttini3 Sonia L Davison1 2 Anita E Wluka3 4 and Susan R Davis1 2 Open Access Women s Health Program Department of Medicine Central and Eastern Clinical School Monash University Alfred Hospital Prahran Victoria Australia 2The Jean Hailes Foundation Clayton Victoria Australia 3Department of Epidemiology and Preventive Medicine Monash University Prahran Australia 4Baker Heart Research Institute AMREP Centre Melbourne Australia Contributed equally Corresponding author Susan R Davis Received 3 Jan 2008 Revisions requested 8 Feb 2008 Revisions received 21 Feb 2008 Accepted 29 Feb 2008 Published 29 Feb 2008 Arthritis Research Therapy 2008 10 R27 doi ar2380 This article is online at http content 10 1 R27 2008 Hanna et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Elevated serum high sensitivity C-reactive protein hsCRP has been reported in established osteoarthritis OA . The aim of this study was to determine whether serum levels of hsCRP are associated with the variation in tibial and patella cartilage volumes in women without evidence of OA. Methods Participants were recruited from a database established from the Australian electoral roll and were aged 40 to 67 years were not hysterectomized and had no significant knee pain or knee injury in the last 5 years. Tibial and patella cartilage volumes were measured from magnetic resonance imaging MRI of each woman s .