tailieunhanh - Báo cáo y học: "What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs. | Available online http content 10 1 R20 Research article What do we know about communicating risk A brief review and suggestion for contextualising serious but rare risk and the example of cox-2 selective and non-selective NSAIDs R Andrew Moore1 Sheena Derry1 Henry J McQuay1 and John Paling2 1Pain Research and Nuffield Department of Anaesthetics University of Oxford Oxford Radcliffe NHS Trust The Churchill Headington Oxford OX3 7LJ UK 2Risk Communication Institute 5822 NW 91st Boulevard Gainesville Florida 32653 USA Corresponding author R Andrew Moore Received 4 Apr 2007 Revisions requested 22 May 2007 Revisions received 6 Dec 2007 Accepted 7 Feb 2008 Published 7 Feb 2008 Arthritis Research Therapy 2008 10 R20 doi ar2373 This article is online at http content 10 1 R20 2008 Moore et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Background Communicating risk is difficult. Although different methods have been proposed - using numbers words pictures or combinations - none has been extensively tested. We used electronic and bibliographic searches to review evidence concerning risk perception and presentation. People tend to underestimate common risk and overestimate rare risk they respond to risks primarily on the basis of emotion rather than facts seem to be risk averse when faced with medical interventions and want information on even the rarest of adverse events. Methods We identified observational studies primarily in the form of meta-analyses with information on individual nonsteroidal anti-inflammatory drug NSAID or selective cyclooxygenase-2 inhibitor coxib use and relative risk of gastrointestinal bleed or .