tailieunhanh - Báo cáo y học: " Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis. | Available online http content 10 1 203 Review Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis Donna M Urquhart1 Cathy Soufan1 Andrew J Teichtahl1 Anita E Wluka1 2 Fahad Hanna1 and Flavia M Cicuttini1 1 Department of Epidemiology and Preventive Medicine Monash University Alfred Hospital Commercial Road Melbourne 3004 Australia 2Baker Heart Research Institute AMREP Centre Commercial Road Melbourne 3004 Australia Corresponding author Donna Urquhart Published 4 February 2008 This article is online at http content 10 1 203 2008 BioMed Central Ltd Arthritis Research Therapy 2008 10 203 doi ar2343 Abstract Studies investigating the effect of physical activity on risk for developing osteoarthritis at weight-bearing joints have reported conflicting results. We examine evidence to suggest that this may be due to the existence of subgroups of individuals who differ in their response to physical activity as well as methodological issues associated with the assessment of knee joint structure and physical activity. Recommendations for future studies of physical activity and the development of knee osteoarthritis are discussed. Introduction It is widely accepted that participation in physical activity is associated with physical psychological and social benefits 1 . Physical activity not only reduces the risk for cardiovascular disease 2 a major cause of mortality in developed countries but is also recommended for the management of obesity and the treatment of mental illness 3 . Globally a vast number of large-scale public health campaigns is aimed at promoting physical activity. Exercise is also widely recommended by health care professionals in the prevention and management of chronic health conditions such as osteoarthritis OA . However our knowledge of the effect of physical activity on risk for developing OA is limited. OA