tailieunhanh - Báo cáo y học: "Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels. | Available online http content 10 3 R57 Research article Leukocyte numbers and function in subjects eating n-3 enriched foods selective depression of natural killer cell levels Violet R Mukaro1 3 Maurizio Costabile1 3 Karen J Murphy2 Charles S Hii1 4 Peter R Howe2 and Antonio Ferrante1 3 4 Open Access Department of Immunopathology Children Youth and Women s Health Service 72 King William Road North Adelaide SA 5006 Australia 2Nutritional Physiology Research Centre School of Health Sciences University of South Australia Adelaide SA 5000 Australia 3School of Pharmaceutical and Medical Sciences University of South Australia Australia Adelaide SA 5000 Australia discipline of Paediatrics University of Adelaide 72 King William Road North Adelaide SA 5006 Australia Corresponding author Antonio Ferrante Received 25 Feb 2008 Revisions requested 14 Mar 2008 Revisions received 18 Mar 2008 Accepted 14 May 2008 Published 14 May 2008 Arthritis Research Therapy 2008 10 R57 doi ar2426 This article is online at http content 10 3 R57 2008 Mukaro et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction While consumption of omega-3 long-chain polyunsaturated fatty acids n-3 LCPUFA has been recommended for those at risk of inflammatory disease such as rheumatoid arthritis the mechanism of their anti-inflammatory effect remains to be clearly defined particularly in relation to the dose and type of n-3 LCPUFA. The objective of this study was to determine whether varying the levels of n-3 LCPUFA in erythrocyte membrane lipids following dietary supplementation is associated with altered numbers and function of circulating leukocytes conducive .