tailieunhanh - Báo cáo y học: "Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss. | Available online http content 9 4 R81 Research article Hand bone loss as an outcome measure in established rheumatoid arthritis 2-year observational study comparing cortical and total bone loss Mari Hoff1 2 Glenn Haugeberg1 3 and Tore K Kvien4 5 Norwegian University of Science and Technology MTFS Department of Neuroscience Division of Rheumatology NO-7489 Trondheim Norway 2Department of Rheumatology St Olav s Hospital University Hospital of Trondheim Olav Kyrres gt 17 N-7006 Trondheim Norway department of Rheumatology Sorlandet Hospital Service box 416 N-4604 Kristiansand S. Norway department of Rheumatology Diakonhjemmet Hospital PB 23 Vinderen N-0319 Oslo Norway 5Faculty of Medicine University of Oslo PB 1072 Blindern N-031 6 Oslo Norway Corresponding author Mari Hoff Received 17 Apr 2007 Revisions requested 25 May 2007 Revisions received 6 Jul 2007 Accepted 17 Aug 2007 Published 17 Aug 2007 Arthritis Research Therapy 2007 9 R81 doi ar2280 This article is online at http content 9 4 R81 2007 Hoff et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by 20 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract The aim of this 2-year longitudinal observational study was to explore hand bone loss as a disease outcome measure in established rheumatoid arthritis RA . A cohort of 215 patients with RA 170 women and 45 men aged 20-70 years were recruited from the Oslo RA registry and studied for changes in hand bone mass during a 2-year follow-up. Digital X-ray radiogrammetry DXR was used to measure cortical hand bone mineral density BMD and metacarpal cortical index whereas dual-energy X-ray absorptiometry DXA was used to assess whole hand BMD which measures total cortical and trabecular bone. .