tailieunhanh - Báo cáo khoa học: " Breast-conserving surgery with or without radiotherapy in women with ductal carcinoma in situ: a meta-analysis of randomized trials"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài:" Breast-conserving surgery with or without radiotherapy in women with ductal carcinoma in situ: a meta-analysis of randomized trials. | Radiation Oncology BioMed Central Open Access Breast-conserving surgery with or without radiotherapy in women with ductal carcinoma in situ a meta-analysis of randomized trials Gustavo A Viani 1 Eduardo J Stefano1 Sérgio L Afonso1 Lígia I De Fendi1 Francisco V Soares1 Paola G Leon2 and Flavio S Guimarães3 Address Department of Radiation Oncology Faculty of Medicine of Marília FAMEMA Marília São Paulo Brazil - Department of Radiation Oncology Instituto Nacional de Enfermedades Neoplásicas Lima Peru and 3Department of Radiation Oncology Hospital São Paulo Brazil Email Gustavo AViani - gusviani@ Eduardo J Stefano - stefano@ Sérgio L Afonso - slafonso@ Lígia I De Fendi - lidefendi@ Francisco V Soares - gusviani@ Paola G Leon - paolaguerrerol@ Flavio S Guimarães - flavioguimaraes@ Corresponding author Published 2 August 2007 Radiation Oncology 2007 2 28 doi 1748-717X-2-28 Received 10 June 2007 Accepted 2 August 2007 This article is available from http content 2 1 28 2007 Viani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background To investigate whether Radiation therapy RT should follow breast conserving surgery in women with ductal carcinoma in situ from breast cancer DCIS with objective of decreased mortality invasive or non invasive recurrence distant metastases and contralateral breast cancer rates. We have done a meta-analysis of these results to give a more balanced view of the total evidence and to increase statistical precision. Methods A meta-analysis of randomized controlled trials RCT was performed comparing RT treatment for DCIS of breast cancer to observation. The MEDLINE EMBASE CANCERLIT .