tailieunhanh - Báo cáo khoa học: " Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy. | Radiation Oncology BioMed Central Open Access Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy Pètra M Braam 1 Judith M Roesink1 Cornells PJ Raaijmakers1 Wim B Busschers2 and Chris HJ Terhaard1 Address Department of Radiotherapy University Medical Center Utrecht Utrecht The Netherlands and - Department of Biostatistics Utrecht University Utrecht The Netherlands Email Pètra M Braam - Judith M Roesink - Cornelis PJ Raaijmakers - Wim B Busschers - Chris HJ Terhaard - Corresponding author Published 05 January 2007 Radiation Oncology 2007 2 3 doi 1748-7I7X-2-3 Received 30 October 2006 Accepted 05 January 2007 This article is available from http content 2 1 3 2007 Braam et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background To describe long-term changes in time of quality of life QOL and the relation with parotid salivary output in patients with head-and-neck cancer treated with radiotherapy. Methods Forty-four patients completed the EORTC-QLQ-C30 3 and the EORTC-QLQ-H N35 questionnaires before treatment 6 weeks 6 months 12 months and at least years after treatment. At the same time points stimulated bilateral parotid flow rates were measured. Results There was a deterioration of most QOL items after radiotherapy compared with baseline with gradual improvement during 5 years follow-up. The specific xerostomia-related items showed improvement in time but did not return to baseline. Global QOL did not alter significantly in

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