tailieunhanh - Báo cáo khoa học: " Salvage for cervical recurrences of head and neck cancer with dissection and interstitial high dose rate brachytherapy"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Salvage for cervical recurrences of head and neck cancer with dissection and interstitial high dose rate brachytherapy. | Radiation Oncology BioMed Central Research Salvage for cervical recurrences of head and neck cancer with dissection and interstitial high dose rate brachytherapy Antonio Cassio Assis Pellizzon 1 João Victor Salvajoli1 Luiz Paulo Kowalski2 and Andre Lopes Carvalho2 Open Access Address Radiation Oncology Department Centro de Tratamento e Pesquisa Hospital ACCamargo São Paulo Brazil and 2Head and Neck Surgery Department Centro de Tratamento e Pesquisa Hospital ACCamargo São Paulo Brazil Email Antonio Cassio Assis Pellizzon - cpellizzon@ João Victor Salvajoli - jvsalv@ Luiz Paulo Kowalski - cpellizzon@ Andre Lopes Carvalho - cpellizzon@ Corresponding author Published 08 August 2006 Received 19 May 2006 Radiation Oncology 2006 1 27 doi 1748-717X-1-27 Accepted 08 August 2006 This article is available from http content l l 27 2006 Pellizzon et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Salvage therapy in head and neck cancer HNC is a controversy issue and the literature is scarce regarding the use of interstitial high-dose rate brachytherapy I-HDR in HNC. We evaluated the long-term results of a treatment policy combining salvage surgery and I-HDR for cervical recurrences of HNC. Charts of 21 patients treated from 1994 to 2004 were reviewed. The crude local control rate for all patients was . The 5- and 8-years overall OS and local relapse-free survival LRFS rates were 50 and respectively. The only predictive factor associated to LFRS and OS was negative margin status p and p . We conclude that complete surgery is mandatory for long term control and the doses given by brachytherapy are not high enough to compensate for