tailieunhanh - Báo cáo khoa học: " Radiation therapy planning with photons and protons for early and advanced breast cancer: an overview"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Radiation therapy planning with photons and protons for early and advanced breast cancer: an overview. | Radiation Oncology BioMed Central Open Access Review Radiation therapy planning with photons and protons for early and advanced breast cancer an overview Damien C Weber 1 2 Carmen Ares1 Antony J Lomax1 and John M Kurtz2 Address Department of Radiation Medicine Paul Scherrer Institute Villigen-PSI Switzerland and 2Department of Radiation Oncology Geneva University Hospital Switzerland Email Damien C Weber - Carmen Ares - Antony J Lomax - John M Kurtz - Corresponding author Published 20 July 2006 Received 16 June 2006 Radiation Oncology 2006 1 22 doi 1748-717X-1-22 Accepted 20 July 2006 This article is available from http content 1 1 22 2006 Weber et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Postoperative radiation therapy substantially decreases local relapse and moderately reduces breast cancer mortality but can be associated with increased late mortality due to cardiovascular morbidity and secondary malignancies. Sophistication of breast irradiation techniques including conformal radiotherapy and intensity modulated radiation therapy has been shown to markedly reduce cardiac and lung irradiation. The delivery of more conformal treatment can also be achieved with particle beam therapy using protons. Protons have superior dose distributional qualities compared to photons as dose deposition occurs in a modulated narrow zone called the Bragg peak. As a result further dose optimization in breast cancer treatment can be reasonably expected with protons. In this review we outline the potential indications and benefits of breast cancer radiotherapy with protons. Comparative planning studies and .

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