tailieunhanh - Báo cáo khoa học: " Dosimetric comparison of intensity-modulated, conformal, and four-field pelvic radiotherapy boost plans for gynecologic cancer: a retrospective planning study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Dosimetric comparison of intensity-modulated, conformal, and four-field pelvic radiotherapy boost plans for gynecologic cancer: a retrospective planning study. | Radiation Oncology BioMed Central Research Open Access Dosimetric comparison of intensity-modulated conformal and four-field pelvic radiotherapy boost plans for gynecologic cancer a retrospective planning study Philip Chan1 3 4 Inhwan Yeo2 3 Gregory Perkins2 Anthony Fyles1 3 4 and Michael Milosevic 1 3 4 Address Department of Radiation Oncology Princess Margaret Hospital-University Health Network Toronto Canada 2Department of Radiation Physics Princess Margaret Hospital-University Health Network Toronto Canada 3Department of Radiation Oncology University of Toronto Toronto Canada and 4Institute of Medical Science University of Toronto Toronto Canada Email Philip Chan - Inhwan Yeo - medicphys@ Gregory Perkins - gregoryperkins_ja@ Anthony Fyles - Michael Milosevic - Corresponding author Published 04 May 2006 Received 21 February 2006 Radiation Oncology 2006 1 13 doi 174 -717X-1-13 Accepted 04 May 2006 This article is available from http content 1 1 13 2006 Chan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Purpose To evaluate intensity-modulated radiation therapy IMRT as an alternative to conformal radiotherapy CRT or 4-field box boost 4FB in women with gynecologic malignancies who are unsuitable for brachytherapy for technical or medical reasons. Methods Dosimetric and toxicity information was analyzed for 12 patients with cervical 8 endometrial 2 or vaginal 2 cancer previously treated with external beam pelvic radiotherapy and a CRT boost. Optimized IMRT boost treatment plans were then developed for each of the 12 patients and compared to CRT and 4FB plans. The plans were .