tailieunhanh - Báo cáo khoa học: " A dosimetric comparison of four treatment planning methods for high grade glioma"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " A dosimetric comparison of four treatment planning methods for high grade glioma. | Radiation Oncology BioMed Central Research A dosimetric comparison of four treatment planning methods for high grade glioma Leor Zach Bronwyn Stall Holly Ning John Ondos Barbara Arora Shankavaram Uma Robert W Miller Deborah Citrin and Kevin Camphausen Open Access Address Radiation Oncology Branch National Cancer Institute 10 Center Drive Building 10 CRC Bethesda MD 20892 USA Email Leor Zach - zachl@ Bronwyn Stall - stallb@ Holly Ning - hning@ John Ondos - ondosj@ Barbara Arora - arorab@ Shankavaram Uma - uma@ Robert W Miller - rwmiller@ Deborah Citrin - citrind@ Kevin Camphausen - camphauk@ Corresponding author Published 21 October 2009 Received 14 July 2009 Accepted 21 October 2009 Radiation Oncology 2009 4 45 doi 1748-717X-4-45 This article is available from http content 4 1 45 2009 Zach et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background High grade gliomas HGG are typically treated with a combination of surgery radiotherapy and chemotherapy. Three dimensional 3D conformal radiotherapy treatment planning is still the main stay of treatment for these patients. New treatment planning methods suggest better dose distributions and organ sparing but their clinical benefit is unclear. The purpose of the current study was to compare normal tissue sparing and tumor coverage using four different radiotherapy planning methods in patients with high grade glioma. Methods Three dimensional conformal 3D sequential boost IMRT integrated boost IB IMRT and Tomotherapy TOMO treatment plans were generated for 20 high grade glioma patients. T1 and T2 MRI abnormalities were used to define

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