tailieunhanh - Báo cáo khoa học: " IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients. | Radiation Oncology BioMed Central Research Open Access IMRT using simultaneously integrated boost SIB in head and neck cancer patients G Studer 1 PU Huguenin1 JB Davis2 G Kunz2 UM Lutolf1 and C Glanzmann1 Address department of Radiation Oncology University Hospital Zurich Switzerland and department of Radiation Physics University Hospital Zurich Switzerland Email G Studer - PU Huguenin - JB Davis - G Kunz - UM Lutolf - C Glanzmann - Corresponding author Published 31 March 2006 Received 22 November 2005 Accepted 31 March 2006 Radiation Oncology2006 1 7 doi 1748-7I7X-I-7 This article is available from http content 1 1 7 2006Studer et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Preliminary very encouraging clinical results of intensity modulated radiation therapy IMRT in Head Neck Cancer HNC are available from several large centers. Tumor control rates seem to be kept at least at the level of conventional three-dimensional radiation therapy the benefit of normal tissue preservation with IMRT is proven for salivary function. There is still only limited experience with IMRT using simultaneously integrated boost SIB-IMRT in the head and neck region in terms of normal tissue response. The aim of this work was 1 to establish tumor response in HNC patients treated with SIB-IMRT and 2 to assess tissue tolerance following different SIB-IMRT schedules. Results Between 1 2002 and 12 2004 115 HNC patients have been curatively treated with IMRT. 70 received definitive IMRT dIMRT 30 were postoperatively irradiated. In 78 concomitant chemotherapy was given. SIB .