tailieunhanh - Báo cáo khoa học: "Simultaneous integrated boost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: "Simultaneous integrated boost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy. | Radiation Oncology BioMed Central Open Access Methodology Simultaneous integrated boost radiotherapy for bilateral breast a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy Giorgia Nicolini Alessandro Clivio Antonella Fogliata Eugenio Vanetti and Luca Cozzi Address Oncology Institute of Southern Switzerland Medical Physics Unit Bellinzona Switzerland Email Giorgia Nicolini - Alessandro Clivio - Antonella Fogliata - afc@ Eugenio Vanetti - Luca Cozzi - lucozzi@ Corresponding author Published 24 July 2009 Received 26 May 2009 Radiation Oncology 2009 4 27 doi 174 -717X-4-27 Accepted 24 July 2009 This article is available from http content 4 1 27 2009 Nicolini et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Purpose A study was performed comparing dosimetric characteristics of volumetric modulated arcs RapidArc RA and fixed field intensity modulated therapy IMRT on patients with bilateral breast carcinoma. Materials and methods Plans for IMRT and RA were optimised for 10 patients prescribing 50 Gy to the breast PTVII Gy fraction and 60 Gy to the tumour bed PTVI Gy fraction . Objectives were for PTVs V90 95 Dmax 107 Mean lung dose MLD 15 Gy V20 Gy 22 heart involvement was to be minimised. The MU and delivery time measured treatment efficiency. Pretreatment dosimetry was performed using EPID and a 2D-array based methods. Results For PTVII minus PTVI V90o was for RA and for IMRT findings are reported as mean 1 standard deviation D5 -D95 homogeneity was Gy RA and Gy IMRT . Conformity index V95 .