tailieunhanh - Báo cáo khoa học: "Successful radiation treatment of anaplastic thyroid carcinoma metastatic to the right cardiac atrium and ventricle in a pacemaker-dependent patient"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Successful radiation treatment of anaplastic thyroid carcinoma metastatic to the right cardiac atrium and ventricle in a pacemaker-dependent patient. | RADIATION ONCOLOGY Successful radiation treatment of anaplastic thyroid carcinoma metastatic to the right cardiac atrium and ventricle in a pacemaker-dependent patient Dasgupta et al. Dasgupta et al. Radiation Oncology 2011 6 16 http content 6 1 16 14 February 2011 2 BioMed Central Dasgupta et al. Radiation Oncology 2011 6 16 http content 6 1 16 RADIATION ONCOLOGY CASE REPORT Open Access Successful radiation treatment of anaplastic thyroid carcinoma metastatic to the right cardiac atrium and ventricle in a pacemaker-dependent patient Tina Dasgupta Igor J Barani Mack Roach III Abstract Anaplastic thyroid carcinoma ATC is a rare aggressive malignancy which is known to metastasize to the heart. We report a case of a patient with ATC with metastatic involvement of the pacemaker leads within the right atrium and right ventricle. The patient survived external beam radiation treatment to his heart with a radiographic response to treatment. Cardiac metastases are usually reported on autopsy to our knowledge this is the first report of the successful treatment of cardiac metastases encasing the leads of a pacemaker and of cardiac metastases from ATCs with a review of the pertinent literature. Background Anaplastic thyroid carcinoma ATC is a rare aggressive malignancy with a median survival of 6 months. Distant metastases - usually to lungs and bone - present early in the course of disease 1 . ATC is also one of the few cancers known to metastasize to the heart 2 . Secondary cardiac tumors are usually reported at autopsy and can involve various anatomic structures of the heart. While cardiac metastases can be treated with external beam radiation cardiac toxicity remains doselimiting and must be taken into consideration during radiation treatment planning for patients with poor cardiac function and pacemaker dependence. We report the case of a patient with ATC who presented with intraventricular metastases encasing the electrical leads .

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