tailieunhanh - Báo cáo khoa học: "Technology Assessment of Automated Atlas Based Segmentation in Prostate Bed Contouring"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Technology Assessment of Automated Atlas Based Segmentation in Prostate Bed Contouring. | Hwee et al. Radiation Oncology 2011 6 110 http content 6 1 110 RADIATION ONCOLOGY RESEARCH Open Access Technology Assessment of Automated Atlas Based Segmentation in Prostate Bed Contouring 1 2 3 2 2 2 Jeremiah Hwee Alexander V Louie Stewart Gaede Glenn Bauman David D Souza Tracy Sexton Michael Lock2 Belal Ahmad2 and George Rodrigues1 2 Abstract Background Prostate bed PB contouring is time consuming and associated with inter-observer variability. We evaluated an automated atlas-based segmentation AABS engine in its potential to reduce contouring time and inter-observer variability. Methods An atlas builder AB manually contoured the prostate bed rectum left femoral head LFH right femoral head RFH bladder and penile bulb of 75 post-prostatectomy cases to create an atlas according to the recent RTOG guidelines. 5 other Radiation Oncologists RO and the AABS contoured 5 new cases. A STAPLE contour for each of the 5 patients was generated. All contours were anonymized and sent back to the 5 RO to be edited as clinically necessary. All contouring times were recorded. The dice similarity coefficient DSC was used to evaluate the unedited- and edited- AABS and inter-observer variability among the RO. Descriptive statistics paired t-tests and a Pearson correlation were performed. ANOVA analysis using logit transformations of DSC values was calculated to assess inter-observer variability. Results The mean time for manual contours and AABS was and minutes respectively p . The DSC results mean SD for the comparison of the unedited-AABS versus STAPLE contours for the PB bladder LFH RFH penile bulb and rectum . The DSC results mean SD for the comparison of the edited-AABS versus STAPLE contours for the PB bladder LFH RFH penile bulb and rectum . The DSC results mean SD for the comparison of the edited-AABS versus the expert .