tailieunhanh - Báo cáo y học: "Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis. | Available online http content 8 5 R143 Research article Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis Heiner Appel1 Christoph Loddenkemper2 Zarko Grozdanovic3 Harald Ebhardt2 Marc Dreimann4 Axel Hempfing4 Harald Stein2 Peter Metz-Stavenhagen4 Martin Rudwaleit1 and Joachim Sieper1 Charité Berlin Campus Benjamin Franklin Department of Gastroenterology Infectiology and Rheumatology Hindenburgdamm 30 1 2200 Berlin Germany 2Charité Berlin Campus Benjamin Franklin Department of Pathology Hindenburgdamm 30 12200 Berlin Germany 3Charite Berlin Campus Benjamin Franklin Department of Radiology Hindenburgdamm 30 1 2200 Berlin Germany 4Werner-Wicker-Klinik Department II Center for Spine Surgery Im Kreuzfeld 4 34537 Bad Wildungen Germany Corresponding author Joachim Sieper TEqual contributors Open Access Received 7 Jun 2006 Revisions requested 17 Jul 2006 Revisions received 1 9 Jul 2006 Accepted 22 Aug 2006 Published 22 Aug 2006 Arthritis Research Therapy 2006 8 R143 doi ar2035 This article is online at http content 8 5 R143 2006 Appel et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Ankylosing spondylitis AS is a chronic inflammatory disease which affects primarily the sacroiliac joints and the spine. In patients with active disease magnetic resonance imaging MRI of the spine shows areas of bone marrow edema the histopathological equivalent of which is unknown. In this study we correlate inflammation in the spine of patients with AS as revealed by histological examination with bone marrow edema as detected by MRI. We have compared the histopathological findings of