tailieunhanh - Báo cáo y học: " Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporar"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporary. | Available online http content 8 4 R106 Research article Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporary Ilse-Gerlinde Sunk1 Siegfried Trattnig2 Winfried B Graninger3 Love Amoyo1 Birgit Tuerk1 Carl-Walter Steiner1 Josef S Smolen1 and Klaus Bobacz1 Open Access Department of Internal Medicine III Division of Rheumatology Medical University of Vienna Waehringer Guertel 1 8-20 A-1 090 Vienna Austria 2Department of Radiology Medical University of Vienna Waehringer Guertel 18-20 A-1090 Vienna Austria 3Medizinische Universitatsklinik Klinische Abteilung fur Rheumatologie LKH Graz Auenbruggerplatz 15 8036 Graz Austria Corresponding author Klaus Bobacz Received 20 Feb 2006 Revisions requested 5 Apr 2006 Revisions received 18 May 2006 Accepted 12 Jun 2006 Published 1 0 Jul 2006 Arthritis Research Therapy 2006 8 R106 doi ar1991 This article is online at http content 8 4 R106 2006 Sunk et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The influence of magnetic resonance imaging MRI devices at high field strengths on living tissues is unknown. We investigated the effects of a 3-tesla electromagnetic field EMF on the biosynthetic activity of bovine articular cartilage. Bovine articular cartilage was obtained from juvenile and adult animals. Whole joints or cartilage explants were subjected to a pulsed 3-tesla EMF controls were left unexposed. Synthesis of sulfated glycosaminoglycans sGAGs was measured by using 35S sulfate incorporation mRNA encoding the cartilage markers aggrecan and type II collagen as well as IL-1P were analyzed by RT-PCR. Furthermore effects of the .

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