tailieunhanh - Báo cáo khoa học: "Gastrointestinal stromal tumor of the stomach with lymph node metastasis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Gastrointestinal stromal tumor of the stomach with lymph node metastasis | BioMed Central World Journal of Surgical Oncology Open Access Case report Gastrointestinal stromal tumor of the stomach with lymph node metastasis Aras Emre Canda 1 Yucel Ozsoy1 Olcay Ak Nalbant2 and Ozgul Sagol3 Address Department of Surgery Manisa State Hospital Manisa Turkey 2Department of Pathology Manisa State Hospital Manisa Turkey and 3Department of Pathology Dokuz Eylul University School of Medicine Izmir Turkey Email Aras Emre Canda - Yucel Ozsoy - dryucelozsoy@ Olcay Ak Nalbant - olcaynalbant@ Ozgul Sagol - Corresponding author Published 5 September 2008 Received 26 April 2008 World Journal of Surgical Oncology 2008 6 97 doi 1477-7819-6-97 Accepted 5 September 2008 This article is available from http content 6 1 97 2008 Canda et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Lymph node LN metastasis of gastrointestinal stromal tumors GIST is unusual. Unlike gastric adenocarcinomas routine lymphadenectomy is not recommended unless there is no suspicion for LN metastasis. Herein we report a case of GIST of the stomach with LN metastasis treated with distal gastrectomy with perigastric LN dissection followed by adjuvant imatinib therapy. Case presentation A 32-year-old female presented with anemia. Diagnostic investigations including thoracoabdominopelvic computed tomography CT scan and gastroscopy revealed a 8 cm gastric antral submucosal tumor without any metastasis. Enlarged periantral LNs were detected during laparotomy and patient underwent distal gastrectomy with en bloc perigastric LN dissection. Pathologic investigation revealed antral stromal tumor with high mitotic and Ki-67 index. Lymph node .