tailieunhanh - Báo cáo y học: "Clinical and functional remission: even though biologics are superior to conventional DMARDs overall success rates remain low – results from RABBIT, the German biologics register"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Clinical and functional remission: even though biologics are superior to conventional DMARDs overall success rates remain low – results from RABBIT, the German biologics register. | Available online http content 8 3 R66 Research article Clinical and functional remission even though biologics are superior to conventional DMARDs overall success rates remain low - results from RABBIT the German biologics register Joachim Listing1 Anja Strangfeld1 Rolf Rau2 Jorn Kekow3 Erika Gromnica-Ihle4 Thilo Klopsch5 Winfried Demary6 Gerd-Rudiger Burmester7 and Angela Zink1 7 German Rheumatism Research Centre Berlin Germany 2Evangelisches Fachkrankenhaus Ratingen Germany 3University of Magdeburg Magdeburg Germany 4Rheumaklinik Berlin-Buch Berlin Germany 5Wilhelm-Kulz-Street 15 Neubrandenburg Germany 6Bahnhofsalle 3-4 Hildesheim Germany 7Charité University Hospital Berlin Germany Contributed equally Corresponding author Joachim Listing Listing@ Received 3 Jan 2006 Revisions requested 23 Jan 2006 Revisions received 13 Feb 2006 Accepted 9 Mar 2006 Published 5 Apr 2006 Arthritis Research Therapy 2006 8 R66 doi ar1 933 This article is online at http content 8 3 R66 2006 Listing et al. licensee BioMed Central Ltd This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract We investigated the frequency of remission according to the disease activity score DAS28 definition modified American Rheumatology Association ARA criteria and the frequency of an achievement of a functional status above defined thresholds functional remission physical independence in rheumatoid arthritis RA patients treated with either biologics or conventional DMARDs. We used the data of a prospective cohort study the German biologics register RABBIT German acronym for Rheumatoid Arthritis - Observation of Biologic Therapy to investigate the outcomes in RA patients with two or more DMARD failures who received new .