tailieunhanh - Báo cáo khoa học: "Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy | BioMed Central World Journal of Surgical Oncology Open Access Case report Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy Margaret I Liang1 and William E Carson III 2 Address 1College of Medicine The Ohio State University Columbus OH USA and 2Division of Surgical Oncology The Ohio State University Columbus oh USA Email Margaret I Liang - William E Carson - Corresponding author Published 27 July 2008 Received 8 April 2008 World Journal of Surgical Oncology 2008 6 79 doi 1477-7819-6-79 Accepted 27 July 2008 This article is available from http content 6 1 79 2008 Liang and Carson licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Lymphazurin 1 blue dye can cause a severe anaphylactic reaction in approximately 1-3 of patients. Case presentation We describe a case of intraoperative anaphylaxis resulting from Lymphazurin 1 blue dye. A 48-year old woman undergoing a mastectomy with sentinel lymph node biopsy experienced a biphasic anaphylactic reaction with two episodes of hypotension at 15 minutes and 2 hours respectively after injection of the blue dye. The late phase was initially refractory to epinephrine. Conclusion Early recognition aggressive hemodynamic management and prolonged monitoring are indicated in these patients to watch for a potential second phase anaphylactic reaction. Background Sentinel lymph node biopsy SLNB has emerged as the standard procedure for staging of the axilla in patients with clinically node-negative breast cancer 1 2 . This procedure serves as an alternative to routine axillary lymph node dissection 3