tailieunhanh - Báo cáo y học: "Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. | Available online http content 7 6 R1404 Open Access Research article Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis En-Pei I Chiang1 Jacob Selhub2 Pamela J Bagley2 Gerard Dallal3 and Ronenn Roubenoff4 5 Department of Food Science and Biotechnology National Chung-Hsing University 250 Kuo-Kuang Road Taichung Taiwan 402 Republic of China 2Vitamin Metabolism Laboratory Jean Mayer USDA Human Nutrition Research Center on Aging Tufts University 711 Washington Street Boston MA 02111 USA 3Biostatistics Unit Jean Mayer USDA Human Nutrition Research Center on Aging Tufts University 711 Washington Street Boston MA 02111 USA 4Nutrition Exercise Physiology and Sarcopenia Laboratory Jean Mayer USDA Human Nutrition Research Center on Aging Tufts University 711 Washington Street Boston MA 02111 USA 5Tufts-New England Medical Center 136 Harrison Avenue Boston MA 02111 USA Corresponding author En-Pei I Chiang chiangisabel@ Received 16 Jun 2005 Revisions requested 9 Aug 2005 Revisions received 6 Sep 2005 Accepted 14 Sep 2005 Published 14 Oct 2005 Arthritis Research Therapy 2005 7 R1404-R1411 DOI ar1839 This article is online at http content 7 6 R1404 2005 Chiang et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Patients with rheumatoid arthritis have subnormal vitamin B6 status both quantitatively and functionally. Abnormal vitamin B6 status in rheumatoid arthritis has been associated with spontaneous tumor necrosis factor TNF -a production and markers of inflammation including C-reactive protein and erythrocyte sedimentation rate. Impaired vitamin B6 status could be a result of .