tailieunhanh - Báo cáo khoa học: "Glycogen-rich clear cell carcinoma of the breast"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Glycogen-rich clear cell carcinoma of the breast | BioMed Central World Journal of Surgical Oncology Case report Open Access Glycogen-rich clear cell carcinoma of the breast Christos Markopoulos Dimitris Mantas T Philipidis Efstatios Kouskos Zoi Antonopoulou ML Hatzinikolaou and Helen Gogas Address Breast Unit 2nd Propedeutic Department of Surgery Athens University Medical School Greece Email Christos Markopoulos - cmarkop@ Dimitris Mantas - dvmantas@ T Philipidis - philipidis@ Efstatios Kouskos - skouskos@ Zoi Antonopoulou - zoianton@ ML Hatzinikolaou - mlhatzinikolaou@ Helen Gogas - hgogas@ Corresponding author Published 29 April 2008 Received 26 November 2007 World Journal of Surgical Oncology 2008 6 44 doi 1477-7819-6-44 Accepted 29 April 2008 This article is available from http content 6 1 44 2008 Markopoulos et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Glycogen-rich carcinoma of the breast is a rare histological subtype of breast cancer usually reported to have poor prognosis. Case presentation We present the case of a 59-year-old woman who underwent a mastectomy for a cm clinically palpable left breast carcinoma originally diagnosed as fibroadenoma on a screening mammogram four years before presentation. Diagnosis of clear cell carcinoma was based on certain histological characteristics of the tumour and immunohistochemical analysis PAS staining keratins AEI AE3 EMA cytokeratin 7 cytokeratin 20 melanosomes vimentin Chromogranin Synaptophysin S-100 SMA . No lymph node metastasis was found and as the tumour was ER positive and PgR negative patient was treated only with an aromatase inhibitor upfront and remains free of disease 48 months now since .