tailieunhanh - Báo cáo y học: " Genetic epidemiology Psoriatic arthritis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Genetic epidemiology Psoriatic arthritis. | Available online http content 4 4 247 Review Genetic epidemiology Psoriatic arthritis Anne C Barton Arthritis Rheumatism Campaign Epidemiology Research Unit University of Manchester UK Corresponding author Anne C Barton e-mail ABarton@ Received 28 September 2001 Revisions received 8 January 2002 Accepted 11 January 2002 Published 31 January 2002 Arthritis Res 2002 4 247-251 2002 BioMed Central Ltd Print ISSN 1465-9905 Online ISSN 1465-9913 Abstract The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis. However a distinct entity is likely to have distinct susceptibility factors in addition to those that contribute to psoriasis and inflammatory arthritis alone. These aetiological factors may be genetic and or environmental and in this review the evidence for distinct psoriatic arthritis genetic susceptibility factors is considered. Keywords gene genetics psoriasis psoriatic arthritis review Introduction Psoriasis is a T-cell-mediated inflammatory disease that affects the skin and occurs in one to two per cent of the general population. In 1964 an association between inflammatory arthritis IA and psoriasis was formally recognised although it was probably first described by Alibert in 1818 1 . The existence of psoriatic arthritis PsA as a distinct clinical entity however remains a topic of debate with some clinicians arguing that it simply represents the coincidental occurrence of psoriasis and inflammatory arthritides such as rheumatoid arthritis RA or ankylosing spondylitis 2 . A review of the investigation of PsA genetic susceptibility factors is therefore both controversial and complex. Community surveys have confirmed the association between IA and psoriasis. For example a cross sectional survey in primary care from North East England has reported a prevalence of psoriasis of and of .

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN
TÀI LIỆU MỚI ĐĂNG
crossorigin="anonymous">
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.