tailieunhanh - Báo cáo khoa học: "Surgical outcomes of borderline breast lesions detected by needle biopsy in a breast screening program"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Surgical outcomes of borderline breast lesions detected by needle biopsy in a breast screening program | Flegg et al. World Journal of Surgical Oncology 2010 8 78 http content 8 1 78 WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Surgical outcomes of borderline breast lesions detected by needle biopsy in a breast screening program Karen M Flegg1 Jeffrey J Flaherty1 Anne M Bicknell2 Sanjiv Jain3 Abstract Background The Australian Capital Territory and South East New South Wales branch of BreastScreen Australia BreastScreen ACT SENSW performs over 20 000 screening mammograms annually. This study describes the outcome of surgical biopsies of the breast performed as a result of a borderline lesion being identified after screening mammography and subsequent workup. A secondary aim was to identify any parameters such as a family history of breast cancer or radiological findings that may indicate which borderline lesions are likely to be upgraded to malignancy after surgery. Methods From a period of just over eight years all patients of BreastScreen ACT SENSW who were diagnosed with a borderline breast lesion were identified. These women had undergone needle biopsy in Breastscreen ACT SENSW and either atypical ductal hyperplasia ADH flat epithelial atypia FEA atypical lobular hyperplasia ALH radial scar complex sclerosing lesion papillary lesion mucocoele-like lesion MLL or lobular carcinoma in situ LCIS was found. Final outcomes for each type of borderline lesion after referral for surgical biopsy were recorded and analysed. Results of the surgical biopsy were compared to the type of needle biopsy and its result radiological findings and family history status. Results Of the 94 surgical biopsies performed due to the presence of a borderline breast lesion 20 showed benign pathology 55 remained as borderline lesions 17 showed non-invasive malignancy and 7 showed invasive malignancy. VALCS biopsy was the most common needle biopsy method used to identify the lesions in this study 76 . Malignant outcomes resulted from 24 of the surgical biopsies with the .