tailieunhanh - Báo cáo khoa học: "Adenoid cystic carcinoma of the peripheral lung: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Adenoid cystic carcinoma of the peripheral lung: a case report | Kitada et al. World Journal of Surgical Oncology 2010 8 74 http content 8 1 74 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Adenoid cystic carcinoma of the peripheral lung a case report 1 1 1 1 2 2 Masahiro Kitada Keisuke Ozawa Kazuhiro Sato Satoshi Hayashi Yoshihiko Tokusashi Naoyuki Miyokawa Tadahiro Sasajima1 Abstract Adenoid cystic carcinoma of the peripheral lung is a rare entity. We recently encountered a patient with adenoid cystic carcinoma. A 75-year-old woman showed a nodular lesion with 10 mm in diameter in the right upper lung field on chest radiography. The diagnosis was unclear but lung cancer could not be ruled out. Thoracoscopic biopsy was performed and intraoperative pathological diagnosis revealed the carcinoma of the lung. We enforced upper lobectomy and mediastinal lymph node dissection to the patient. Histopathological examination revealed adenoid cystic carcinoma with a characteristic cribriform structure. Immunohistochemical examination revealed that the tumor cells were positive for thyroid transcription factor 1 TTF-1 this tumor was diagnosed primary ACC of the lung. Background Adenoid cystic carcinoma ACC of the lung is a relatively rare lung cancer arising from the bronchial glands and accounting for about of all lung cancers 1 2 . ACC has a slow growing and prolonged clinical course and thus is considered a low-grade malignancy. The site of origin is the tracheobronchial glands so ACC is more common in the central bronchi than in the segmental bronchi. Reports of ACC originating in the peripheral lung are rare. In addition in cases of occurrence in the periphery lung metastases from a salivary gland tumor must be ruled out. It reports a case of ACC which we experienced. Case A 75-year-old woman showed a nodular lesion in the right upper lung field on the chest radiography with 6 mm diameter. After 1 year of observation follow-up chest radiography showed an increase in size to 10 mm. In the thorough .