tailieunhanh - Báo cáo khoa học: "Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy | Jadav et al. World Journal of Surgical Oncology 2010 8 54 http content 8 1 54 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy Alka M Jadav 1 Sri GThrumurthy 1 2 and Bernard A DeSousa3 Abstract Late colonic metastasis following curative surgery for renal cell carcinoma has rarely been described. We present the first reported case of solitary colonic renal cell carcinoma metastasis presenting as an intra-abdominal bleed nine years post-nephrectomy. Background The worldwide incidence of renal cell carcinoma RCC is approximately 209 000 new cases per year with a mortality of 102 000 deaths per year. This accounts for 3 of all adult malignancies. Metastatic disease may be present in up to 25 of patients at the time of diagnosis 1 2 . Intestinal metastasis from RCC is uncommon. The commonest site of distant metastasis in 1451 autopsy cases with RCC was in the lungs 76 followed by lymph nodes bones and liver 3 . RCC very rarely metastasizes to the colon - a comprehensive Medline search revealed only 7 reported cases to date of post-nephrectomy colonic metastasis from RCC 4-10 . This case represents the first incidence of late colonic RCC metastasis presenting as a surgical emergency in the way of an intraabdominal bleed. Case Presentation A 65-year-old woman presented to casualty with acute abdominal pain and collapse. The only significant history was of a left nephrectomy for clear cell renal carcinoma nine years previously from which she had made a full recovery recently being discharged from further followup. The patient recalled that her RCC had been excised with tumour-free margins - no further information was available. Examination revealed generalised abdominal tenderness with a normal haemoglobin of g dL. Portable Correspondence srigan@ 1 Department of Lower Gastrointestinal Surgery Royal Preston Hospital .

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