tailieunhanh - Báo cáo khoa học: "Isolated pancreatic metastasis from rectal cancer: a case report and review of literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Isolated pancreatic metastasis from rectal cancer: a case report and review of literature | Lee et al. World Journal of Surgical Oncology 2010 8 26 http content 8 1 26 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Isolated pancreatic metastasis from rectal cancer a case report and review of literature 1 2 1 1 1 1 1 Chao-Wei Lee Ren-Chin Wu Jun-Te Hsu Chun-Nan Yeh Ta-Sen Yeh Tsann-Long Hwang Yi-Yin Jan Miin-Fu Chen1 Abstract Isolated pancreatic metastases from a non-pancreatic primary malignancy are very rare. Studies have shown that resection of metastases is of proven benefit in some types of tumors. We report a case of 76-year-old Taiwanese woman with rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and abdominoperineal resection 2 years ago presenting with an asymptomatic mass at the pancreatic tail on a routine follow up abdominal computed tomography scan. The patient underwent distal pancreatectomy and splenectomy under the preoperative impression of a primary pancreatic malignancy. Histological examination of the surgical specimen showed metastatic adenocarcinoma. Immunohistochemical studies confirmed the diagnosis of pancreatic metastasis from rectal adenocarcinoma. Postoperative chemotherapy in the form of oral capecitabine was given. The patient is alive and disease free 12 months after the surgery. In a patient presenting with a pancreatic mass with history of a non-pan-creatic malignancy a differential diagnosis of pancreatic metastasis should be considered. Surgical resection of a solitary pancreatic mass is justified not only to get the definitive diagnosis but also to improve the survival. Background The common sites of metastasis from colorectal adenocarcinoma are the liver lung and regional lymph nodes 1 . Colorectal adenocarcinoma however rarely metastasize to the pancreas. Isolated pancreatic metastases from non-pancreatic primary tumors are very rare accounting for approximately 2 of all pancreatic neoplasms 2 . Renal cell carcinoma is the most common primary malignancy to metastasize to the .