tailieunhanh - Báo cáo khoa học: Plant oxylipins: COI1/JAZs/MYC2 as the core jasmonic acid-signalling module

Jasmonic acid (JA) and its derivates, collectively known as jasmonates (JAs), are essential signalling molecules that coordinate the plant response to biotic and abiotic challenges, in addition to several developmental pro-cesses. The COI1 F-box and additional SCF modulators have long been known to have a crucial role in the JA-signalling pathway. | MINIREVIEW Plant oxylipins COI1 JAZs MYC2 as the core jasmonic acid-signalling module Andrea Chini Marta Boter and Roberto Solano Departamento de Genetica Molecular de Plantas Centro Nacionalde Biotecnologia-CSIC Madrid Spain Keywords arabidopsis COI1 hormone response Jas domain jasmonate signalling JAZ repressors MYC2 transcription factors ZIM domain Correspondence R. Solano Departamento de Genetica Molecular de Plantas Centro Nacional de Biotecnologia-CSIC Campus Universidad Autonoma 28049 Madrid Spain Fax 34 91 585 4506 Tel 34 91 585 5429 E-mail rsolano@ Jasmonic acid JA and its derivates collectively known as jasmonates JAs are essential signalling molecules that coordinate the plant response to biotic and abiotic challenges in addition to several developmental processes. The COI1 F-box and additional SCF modulators have long been known to have a crucial role in the JA-signalling pathway. Downstream JA-dependent transcriptional re-programming is regulated by a cascade of transcription factors and MYC2 plays a major role. Recently JAZ family proteins have been identified as COI1 targets and repressors of MYC2 defining the missing link in JA signalling. JA-Ile has been proposed to be the active form of the hormone and COI1 is an essential component of the receptor complex. These recent discoveries have defined the core JA-signal-ling pathway as the module COI1 JAZs MYC2. Received 7 November 2008 revised 3 February 2009 accepted 20 February 2009 doi Introduction Plants are sessile organisms that need to adapt to their constantly changing environment. The specific plant response to a particular stimulus crucial for its survival and fitness is mediated by a complex hormonal network. Jasmonates JAs are essential signalling molecules modulating the plant response to biotic and abiotic stresses as well as several growth and developmental traits 1-4 . In general JAs help to modulate the competitive allocation of plant energy .