tailieunhanh - báo cáo khoa học: "A massive abdominal wall desmoid tumor occurring in a laparotomy scar: A case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A massive abdominal wall desmoid tumor occurring in a laparotomy scar: A case report | Wanjeri and Opeya World Journal of Surgical Oncology 2011 9 35 http content 9 1 35 5 t WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access A massive abdominal wall desmoid tumor occurring in a laparotomy scar A case report Joseph K Wanjeri Collins JO Opeya Abstract Introduction Desmoid tumors are benign but locally aggressive tumors of mesenchymal origin which are poorly circumscribed infiltrate the surrounding tissue lack a true capsule and are composed of abundant collagen. History of trauma to the site of tumor origin is elicited in up to 1 in 4 cases and they most commonly develop in the anterior abdominal wall and shoulder girdle but they can arise in any skeletal muscle. The clinical behavior and natural history of desmoid tumors are unpredictable and management is difficult with many issues remaining controversial mainly regarding early detection the role type and timing of surgery and the value of non-operative therapies. Case presentation We report a case of a 23 year old male referred from a district hospital to a national referral hospital in Kenya after developing a huge abdominal wall desmoid tumor following laparotomy for a blunt abdominal injury fourteen months earlier. The tumor was successfully excised and the abdominal wall defect reconstructed using a vicryl prolene mesh and a unilateral groin flap. The patient had a non-eventful recovery and was discharged through radiotherapy clinic. Conclusion Wide margin tumor excision alone is a reasonable option in the management of desmoid tumors. Introduction Desmoid tumors account for of all neoplasms and less than 3 of all soft tissue tumors with the estimated incidence in the general population being 2-4 per million of population per year 1-3 . Affected patients mostly fall within the age range 10-40 years with those younger than 10 years or older than 44 being affected rarely 1 . The myofibroblast is the cell considered responsible for the development of desmoid tumors but the