tailieunhanh - báo cáo khoa học: "Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer | Dooley et al. World Journal of Surgical Oncology 2011 9 30 http content 9 1 30 5 t WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Surgical perspectives from a prospective nonrandomized multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer yA illi m Pimm lax i Tar A In n2 k m Hi 7 Pint A l 2Ì C H H i3 Po ri I I c Erst r if ocr 2 f f i4 R I i 73 Hcithi Tifn5 6 I P x iH Ro2i f 7 William C Dooley Ozer Algdn Kdmbiz Dowldisildlli Ddrius rldl icescdttl Elizdbeui Tito J Ddvid BedLiy Art G Lerner8 Betsy Bdlldrd9 Susdn K Boolbol10 Abstract Background Accelerated pdrtidl bredst irrddidtion APBI mdy be used to deliver rddidtion to the tumor bed postlumpectomy in eligible pdtients with bredst cdncer. Pdtient dnd tumor cUdrdcteristics ds well ds the lumpectomy technique cdn influence pdtient eligibility for APBI. This report describes d lumpectomy procedure dnd exdmines pdtient tumor dnd surgicdl chdrdcteristics from d prospective multicenter study of electronic brachytherapy. Methods The study enrolled 65 pdtients of dge 45-84 yedrs with ductdl cdrcinomd or ductdl cdrcinomd in situ dnd 44 pdtients who met the inclusion dnd exclusion criterid were tredted with APBI using the Axxent electronic brachytherapy system following lumpectomy. The prescription dose wds 34 Gy in 10 fractions over 5 ddys. Results The lumpectomy technique ds described herein vdried by site dnd pdtient chdrdcteristics. The bdlloon dpplicdtor wds impldnted by the surgeon 91 or d rddidtion oncologist 9 during or up to 61 ddys postlumpectomy medn 22 ddys . A ldterdl dpprodch wds most commonly used 59 for insertion of the dpplicdtor followed by dn incision site dpprodch in 27 of cdses d medidl dpprodch in 5 dnd dn inferior dpprodch in 7 . A trocdr wds used during dpplicdtor insertion in 27 of cdses. Locdl dnesthetic seddtion both or neither were ddministered in 45 2 41 dnd 11 of cdses respectively during dpplicdtor pldcement.