tailieunhanh - báo cáo khoa học: "Malignant fibrous histiocytoma originating from the mesorectum: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Malignant fibrous histiocytoma originating from the mesorectum: a case report | Nakayama et al. World Journal of Surgical Oncology 2011 9 15 http content 9 1 15 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Malignant fibrous histiocytoma originating from the mesorectum a case report Yoshifumi Nakayama Noritaka Minagawa Takayuki Torigoe Koji Yamaguchi Abstract Background Malignant fibrous histiocytoma MFH is a common sarcoma affecting soft tissues of the body especially of the extremities or trunk. Prognosis of the abdominal MFH is usually poor. Case presentation A 52-year-old female presented to our surgical outpatient clinic with a lower abdominal tumor that had been gradually increasing in size. Clinical examination revealed a firm irregularly surfaced fixed painless child-head-sized tumor located in her lower abdomen. Computed tomography CT and magnetic resonance imaging MRI of the abdomen revealed a polycystic tumor at the lower abdomen which was 15 X 13 X 11 cm in diameter and encased the colorectum to the left back side. A barium enema and a colonoscopy showed direct invasion to the rectum. In 2001 the tumor had been excised along with a low anterior resection of the rectum because of direct invasion. The origin of this tumor was the mesorectum. The weight of the excised tumor was 1 500 g including 800 ml of a brown fluid. A histopathological diagnosis revealed a common type of MFH in which mitotic figures are frequently seen. Conclusion This patient has survived without recurrence for approximately 8 years since the completed tumor resection. It is important to obtain a complete resection during the MFH treatment. Background Malignant fibrous histiocytoma MFH is a common sarcoma affecting soft tissues of the body especially of the extremities or trunk 1-3 . The tumor cells are derived from histiocytes capable of fibroblastic transformation 4 . MFH is an aggressive tumor with a high potential of demonstrating metastasis to other parts of the body. The prognosis of patients with abdominal MFH is usually poor 5 .