tailieunhanh - báo cáo khoa học: "Synchronous double primary malignant tumor of the gallbladder and liver: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Synchronous double primary malignant tumor of the gallbladder and liver: a case report | Kim et al. World Journal of Surgical Oncology 2011 9 84 http content 9 1 84 5 t WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Synchronous double primary malignant tumor of the gallbladder and liver a case report Ji Won Kim1 Jae Woong Han1 So Young Jung1 Jae Pil Jung1 and Jeong Won Kim2 Abstract We report a case of synchronous double primary tumor of gallbladder and liver. A 63-year-old male was admitted to the hospital complaining of abdominal discomfort. Enhanced computed tomography of the abdomen showed acute cholecystitis with tiny gallbladder stones and a cm size enhanced nodule in the left lobe of the liver. Under the impression of acute cholecystitis with gall bladder stones and hepatocellular carcinoma of the left Liver the patient underwent a laparotomy. At laparotomy a mass was palpated on the surface of the neck portion of the gall bladder. Intraoperative frozen diagnosis revealed adenocarcinoma of the gall bladder. The patient was diagnosed as having gall bladder cancer and hepatocellular carcinoma so extended cholecystectomy with dissection of regional lymph nodes and left hemihepatectomy were performed. Histological examination revealed moderated differentiated adenocarcinoma of gallbladder and hepatocellular carcinoma of liver. To our knowledge the simultaneous occurrence of primary malignant tumor of the gallbladder and liver has never been published before. The patient is doing well with no evidence of recurrence 17 months after surgery. Keywords Hepatocellular carcinoma Gallbladder cancer synchronous double primary malignant tumor Background Synchronous double primary malignant neoplasms are a secondary malignancy occurring at the same time or within 6 months after the first malignancy. Improvement of survival rates for patients with malignancy due to early diagnosis and new treatments has enabled more patients to survive long enough to develop the subsequent primary malignancy and development of more sophisticated .