tailieunhanh - Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: 4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004. | Available online http content 6 4 155 Meeting report 4th meeting of the EU research network EUROME From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis London UK 9 March 2004 Saleh Ibrahim1 and Ewa M Paleolog2 Institute of Immunology Medical Faculty University of Rostock Germany 2Kennedy Institute of Rheumatology Faculty of Medicine Imperial College London UK Corresponding author Ewa Paleolog Received 6 May 2004 Accepted 19 May 2004 Published 18 June 2004 Arthritis Res Ther 2004 6 155-158 DOI ar1200 2004 BioMed Central Ltd Abstract Rheumatoid arthritis RA is a common human disease with a prevalence of about 1 in most parts of the world. At the time of symptom onset it is difficult to predict the severity of subsequent disease course. After 2 years joint erosions are seen in most patients and most patients become clinically disabled within 20 years. A recent meeting at the Kennedy Institute of Rheumatology Imperial College London brought together representatives from several European centres of excellence to discuss research funded by the EU Framework 5 Quality of Life Programme. This research network combines gene and protein expression profiling with different animal models of RA to identify cells genes and pathways contributing to arthritis initiation progression and chronicity. The studies discussed highlight the reality that collaboration between different research groups is the basis of groundbreaking research and it is hoped eventual new therapies for RA. Keywords arthritis genomics therapy Introduction Rheumatoid arthritis RA is a chronic systemic inflammatory disease of unknown aetiology and is one of the most common causes of disability in the Western world. The research network EUROME http supported by the EU Framework 5 Quality of Life and Management of Living Resources Programme .