tailieunhanh - Báo cáo y học: "Deep transcranial magnetic stimulation for the treatment of auditory hallucinations: a preliminary open-label study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Deep transcranial magnetic stimulation for the treatment of auditory hallucinations: a preliminary open-label study. | Rosenberg et al. Annals of General Psychiatry 2011 10 3 http content 10 1 3 ANNALS OF GENERAL PSYCHIATRY PRIMARY RESEARCH Open Access Deep transcranial magnetic stimulation for the treatment of auditory hallucinations a preliminary open-label study Oded Rosenberg1 Yiftach Roth1 Moshe Kotler1 Abraham Zangen2 Pinhas Dannon1 Abstract Background Schizophrenia is a chronic and disabling disease that presents with delusions and hallucinations. Auditory hallucinations are usually expressed as voices speaking to or about the patient. Previous studies have examined the effect of repetitive transcranial magnetic stimulation TMS over the temporoparietal cortex on auditory hallucinations in schizophrenic patients. Our aim was to explore the potential effect of deep TMS using the H coil over the same brain region on auditory hallucinations. Patients and methods Eight schizophrenic patients with refractory auditory hallucinations were recruited mainly from Beer Ya akov Mental Health Institution Tel Aviv university Israel ambulatory clinics as well as from other hospitals outpatient populations. Low-frequency deep TMS was applied for 10 min 600 pulses per session to the left temporoparietal cortex for either 10 or 20 sessions. Deep TMS was applied using Brainsway s H1 coil apparatus. Patients were evaluated using the Auditory Hallucinations Rating Scale AHRS as well as the Scale for the Assessment of Positive Symptoms scores SAPS Clinical Global Impressions CGI scale and the Scale for Assessment of Negative Symptoms SANS . Results This preliminary study demonstrated a significant improvement in AHRS score an average reduction of and to a lesser extent improvement in SAPS results an average reduction of . Conclusions In this study we have demonstrated the potential of deep TMS treatment over the temporoparietal cortex as an add-on treatment for chronic auditory hallucinations in schizophrenic patients. Larger samples in a .