tailieunhanh - Báo cáo y học: "Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium. | Available online http content 11 1 R13 Research article Elevated expression of caspase-3 inhibitors survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium Anak ASSK Dharmapatni1 Malcolm D Smith2 David M Findlay3 Christopher A Holding1 Andreas Evdokiou3 Michael J Ahern2 Helen Weedon2 Paul Chen4 Gavin Screaton5 Xiao N Xu4 and David R Haynes1 1 Discipline of Pathology School of Medical Sciences Faculty of Health Sciences University of Adelaide North Terrace Adelaide 5005 South Australia Australia 2Rheumatology Research Unit Repatriation General Hospital Daws Road Adelaide 5041 South Australia Australia 3Discipline of Orthopaedics and Trauma School of Medicine Faculty of Health Sciences University of Adelaide and Hanson Institute Frome Road Adelaide 5005 South Australia Australia 4MRC Human Immunology Unit Weatherall Institute of Molecular Medicine John Radcliffe Hospital Oxford OX3 UK 5Hammersmith Hospital Du Cane Road London W12 0NN UK Corresponding author David R Haynes Received 20 Jun 2008 Revisions requested 23 Jul 2008 Revisions received 2 Dec 2008 Accepted 27 Jan 2009 Published 27 Jan 2009 Arthritis Research Therapy 2009 11 R13 doi ar2603 This article is online at http content 11 1 R13 2009 Dharmapatni et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Tumour necrosis factor-related apoptosisinducing ligand TRAIL is a tumour necrosis factor TNF family member capable of inducing apoptosis in many cell types. Methods Using immunohistochemistry terminal deoxynucleotidyl transferase biotin-dUTP nick end labelling TUNEL and real-time PCR we investigated the expression of .

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