tailieunhanh - báo cáo hóa học:" High rate of loss to clinical follow up among African HIV-infected patients attending a London clinic: a retrospective analysis of a clinical cohort"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : High rate of loss to clinical follow up among African HIV-infected patients attending a London clinic: a retrospective analysis of a clinical cohort | Gerver et al. Journal of the International AIDS Society 2010 13 29 http content 13 1 29 JOURNALOF THE INTERNATIONAL AIDS SOCIETY RESEARCH Open Access High rate of loss to clinical follow up among African HIV-infected patients attending a London clinic a retrospective analysis of a clinical cohort 13 2 12 2 1 Sarah M Gerver 1 Tim R Chadborn Fowzia Ibrahim Bela Vatsa Valerie C Delpech Philippa J Easterbrook Abstract Background Long-term regular clinic follow up is an important component of HIV care. We determined the frequency and characteristics of HIV-infected patients lost to follow up from a London HIV clinic and factors associated with loss to all HIV follow up in the UK. Methods We identified 1859 HIV-infected adults who had registered and attended a London clinic on one or more occasions between January 1997 and December 2005. Loss to follow up was defined as clinic non-attendance for one or more years. Through anonymized linkage with the Survey of Prevalent HIV Infections Diagnosed and Health Protection Scotland national databases of all HIV patients in care in the UK up to December 2006 loss-to-follow-up patients were categorized as Transfers subsequently received care at another UK HIV clinic or UKLFU no record of subsequent attendance at any HIV clinic in the UK . Logistic regression analysis was used to identify factors associated with UKLFU for those both on highly active antiretroviral therapy HAART and not on HAART. Results In total 722 of 1859 patients were defined as lost to follow up. Of these 347 were Transfers and 375 or of all patients were UKLFU. Overall of all patients receiving HAART and not receiving HAART were UKLFU. Among those on HAART risk factors for UKLFU were African heterosexual female OR 95 CI versus white men who have sex with men earlier year of HIV clinic registration 1997-1999 OR 95 CI 2000-02 OR 95 CI vs. 2003-2005 CD4 count of 200 .