tailieunhanh - báo cáo hóa học:" HIV infection and sexual risk behaviour among youth who have experienced orphanhood: systematic review and meta-analysis"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : HIV infection and sexual risk behaviour among youth who have experienced orphanhood: systematic review and meta-analysis | Operario et al. Journal of the International AIDS Society 2011 14 25 http content 14 1 25 JOURNALOF THE INTERNATIONAL AIDS SOCIETY RESEARCH Open Access HIV infection and sexual risk behaviour among youth who have experienced orphanhood systematic review and meta-analysis Don Operario1 Kristen Underhill1 Carolyn Chuong1 and Lucie Cluver2 Abstract Background Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and HIV risk in studies of youth aged 24 years and younger. Methods Using systematic review methodology we identified 10 studies reporting data from 12 countries comparing orphaned and non-orphaned youth on HIV-related risk indicators including HIV serostatus other sexually transmitted infections pregnancy and sexual behaviours. We meta-analyzed data from six studies reporting prevalence data on the association between orphan status and HIV serostatus and we qualitatively summarized data from all studies on behavioural risk factors for HIV among orphaned youth. Results Meta-analysis of HIV testing data from 19 140 participants indicated significantly greater HIV seroprevalence among orphaned compared with non-orphaned youth odds ratio 95 confidence interval . Trends across studies showed evidence for greater sexual risk behaviour in orphaned youth. Conclusions Studies on HIV risk in orphaned populations which mostly include samples from sub-Saharan Africa show nearly two-fold greater odds of HIV infection among orphaned youth and higher levels of sexual risk behaviour than among their non-orphaned peers. Interventions to reduce risk for HIV transmission in orphaned youth are needed to address the sequelae of parental illness and death that might contribute to sexual risk and HIV infection. Background One of the many consequences of the global HIV epidemic is the impact of adult

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