tailieunhanh - Báo cáo y học: "A short review on the aetiology and pathophysiology of alcoholism"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: A short review on the aetiology and pathophysiology of alcoholism. | Annals of General Psychiatry BioMed Central Open Access Review A short review on the aetiology and pathophysiology of alcoholism George Moussas Christos Christodoulou and Athanassios Douzenis Address Second Psychiatry Department Athens University Medical School Attikon General Hospital Athens Greece Email George Moussas - gmpsuoa@ Christos Christodoulou - gchristodoulou@ Athanassios Douzenis -thandouz@ Corresponding author Published 14 May 2009 Received 22 January 2009 Annals of General Psychiatry 2009 8 10 doi l744-859X-8-l 0 Accepted 14 May 2009 This article is available from http content 8 l 10 2009 Moussas et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Alcoholism is a chronic remitting and relapsing condition its aetiology and pathophysiology remains largely obscure despite recent advances. This review summarises the current knowledge about the causation biological or psychological of alcohol addiction. This involves heredity candidate genes alcohol metabolism regulation and the influence of alcohol in the pathophysiology of the different neurotransmitter systems. Alcohol addiction is a multifactorial phenomenon where personality structure individual state of mind and social influences are in constant interaction with brain neurobiology and pathophysiology. This disorder influences different sexes in different ways and causes major problems especially in developed societies. Background It is well established that alcoholism is a chronic condition and a major public health issue. Alcoholism presents as a continuum with different presentations among .