tailieunhanh - VIRAL GENE THERAPY

The general meaning of gene therapy is to correct defective genes that are responsible for disease development. The most common form of gene therapy involves the insertion, alteration or removal of genes within an individual's cells and biological tissues. Many of gene transfer vectors are modified viruses. The ability for the delivery of therapeutic genes made them desirable for engineering virus vector systems. Recently, the viral vectors in laboratory and clinical use have been based on RNA and DNA viruses processing very different genomic structures and host ranges. Various viral vectors have been developed and optimized, such as retrovirus, adenovirus, lentivirus and adeno-associated virus. This book provides broad. | VIRAL GENE THERAPY Edited by Ke Xu Viral Gene Therapy Edited by Ke Xu Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Romina Krebel Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright Steve Mann 2010. Used under license from First published July 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Viral Gene Therapy Edited by Ke Xu p. cm. ISBN 978-953-307-539-6 ikrrr iJ OPEN ACCESS INI Evn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .