tailieunhanh - Báo cáo khoa học: "Season of birth, clinical manifestations and Dexamethasone Suppression Test in unipolar major depression"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Season of birth, clinical manifestations and Dexamethasone Suppression Test in unipolar major depression. | Annals of General Psychiatry BioMed Central Primary research Season of birth clinical manifestations and Dexamethasone Suppression Test in unipolar major depression Konstantinos N Fountoulakis 1 Apostolos lacovides1 Michael Karamouzis2 George S Kaprinis1 and Charalambos Ierodiakonou1 Open Access Address Third Department of Psychiatry Aristotle University of Thessaloniki Greece and laboratory of Biochemistry Aristotle University of Thessaloniki Greece Email Konstantinos N Fountoulakis - kfount@ Apostolos lacovides - iacovid@ Michael Karamouzis - mkaram@ George S Kaprinis - kaprinis@ Charalambos lerodiakonou - kfount@ Corresponding author Published 3 August 2007 Received 9 March 2007 Annals of General Psychiatry 2007 6 20 doi 1744-859X-6-20 Accepted 3 August 2007 This article is available from http content 6 1 20 2007 Fountoulakis et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Reports in the literature suggest that the season of birth might constitute a risk factor for the development of a major psychiatric disorder possibly because of the effect environmental factors have during the second trimester of gestation. The aim of the current paper was to study the possible relationship of the season of birth and current clinical symptoms in unipolar major depression. Methods The study sample included 45 DSM-IV major depressive patients and 90 matched controls. The SCAN v. Hamilton Depression Rating Scale HDRS and Hamilton Anxiety Scale HAS were used to assess symptomatology and the I mg Dexamethasone Suppression Test DST was used to subcategorize patients. Results Depressed patients as a whole did not .