tailieunhanh - PEGylated Protein Drugs: Basic Science and Clinical Applications

The collected Chapters in this volume describe the current status of poly(ethylene glycol) (PEG) modification of proteins, peptides, oligonucleotides and small molecule drugs, the recent advances in conjugation chemistry, and new clinical products. The book provides an excellent update in this rapidly evolving field, and the comprehensive collection of Chapters complements well past reviews/volumes that have documented the evolution of PEGylation. For example, a reader new to this field is encouraged to gain the historical perspective by reading the following reviews [1–8]. Only then is it possible to see just how far this field has come and understand that it has already established a new class of therapeutics as. | BIRKHAUSER Milestones in Drug Therapy Michael J. Parnham Jacques Bruinvels Series. Editors PEGylated Protein Drugs Basic Science and Clinical Applications LoiejBioioj Francesco M. Veronese Editor BIRKHAUSER Milestones in Drug Therapy MDT Series Editors Prof. Dr. Michael J. Parnham PhD Director of Preclinical Discovery Centre of Excellence in Macrolide Drug Discovery GlaxoSmithKline Research Centre Zagreb Ltd. Prilaz baruna Filipovica 29 HR-10000 Zagreb Croatia Prof. Dr. J. Bruinvels Sweelincklaan 75 NL-3723 JC Bilthoven The .