tailieunhanh - PRENATAL DIAGNOSIS AND SCREENING FOR DOWN SYNDROME

Viruses are obligate parasites which depend on living cells to multiply. Their ability to deliver stable RNA and DNA into cells has determined their use in gene therapy. In 1983 Mann et al. developed one of the first retroviral gene therapy vectors for delivery in vitro (Mann, Mulligan et al. 1983). This development was followed by many successfully gene therapy trials of retroviruses (Anderson, Blaese et al. 1990; Levine and Friedmann 1991; Blaese, Culver et al. 1993). Now, retrovirual vectors are implemented in nearly of clinical trials ([June 2010]). Retroviruses belong to the Retroviriade family | PRENATAL DIAGNOSIS AND SCREENING FOR DOWN SYNDROME Edited by Subrata Dey Prenatal Diagnosis and Screening for Down Syndrome Edited by Subrata Dey Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Romina Krebel Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright Richard A. Abplanalp 2010. Used under license from First published August 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Prenatal Diagnosis and Screening for Down Syndrome Edited by Subrata Dey p. cm. ISBN 978-953-307-355-2 ikrrr iJ OPEN ACCESS INI Cvn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .

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• Neuropsychiatric Manifestations
• AIDS and Trauma
• Cutaneous Manifestations
• Sub Sahara African
• Benign and Malignant
• Lymphoproliferative Disorders
• carefully monitored
• branded generic
• disease programmes
• Cutaneous Manifestation
• cancer registry