tailieunhanh - AUTISM –  A NEURODEVELOPMENTAL  JOURNEY FROM GENES TO BEHAVIOUR  

In the kidney, Th17 effector cells have been demonstrated in biopsy samples in human glomerulonephritis (Abdulahad et al. 2009) and may participate in the pathogenesis of proliferative glomerulonephritis via production of IL-17 and direct induction of renal inflammation (Kim et al. 2009; Miossec et al. 2009; Turner et al. 2010; Kitching and Holdsworth 2011). Recent studies utilizing genetically engineered mice showed that RORγt promotes the development of crescentic glomerulonephritis by directing nephritogenic Th17 responses (Steinmetz et al. 2011) . In contrast, the adaptive immune response by T cells is regulated by T regulatory cell (Treg)s (Jiang and Chess 2006). Treg cells are in charge of suppressing potentially deleterious activities. | AUTISM - A NEURODEVELOPMENTAL JOURNEY FROM GENES TO BEHAVIOUR Edited by Valsamma Eapen Autism - A Neurodevelopmental Journey from Genes to Behaviour Edited by Valsamma Eapen Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Marina Jozipovic Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright A pyro Design 2010. Used under license from First published August 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Autism - A Neurodevelopmental Journey from Genes to Behaviour Edited by Valsamma Eapen p. cm. ISBN 978-953-307-493-1 ikrrr iJ OPEN ACCESS INI Cvn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .