tailieunhanh - Takigami et al. Journal of Orthopaedic Surgery and Research 2010, 5:33

Takigami et al. Journal of Orthopaedic Surgery and Research 2010, 5:33 CASE REPORT Case report Open Access Functional bracing for delayed union of a femur fracture associated with Paget's disease of the bone in an Asian patient: a case report Iori Takigami*1, Akira Ohara1, Kazu Matsumoto1, Masashi Fukuta2 and Katsuji Shimizu1 Abstract Paget's disease of the bone is a common metabolic bone disease in most European countries, Australia, New Zealand, and North America. Conversely, this disease is rare in Scandinavia, Asia, and Africa. In Japan, it is extremely rare, with a prevalence of . Paget's disease is a localized disorder of bone remodeling. Excessive bone. | Takigami et al. Journal of Orthopaedic Surgery and Research 2010 5 33 http content 5 1 33 éHMÌ JOURNAL OF ORTHOPAEDIC MBs SURGERY AND RESEARCH CASE REPORT Open Access Functional bracing for delayed union of a femur fracture associated with Paget s disease of the bone in an Asian patient a case report lori Takigami 1 Akira Ohara1 Kazu Matsumoto1 Masashi Fukuta2 and Katsuji Shimizu1 Abstract Paget s disease of the bone is a common metabolic bone disease in most European countries Australia New Zealand and North America. Conversely this disease is rare in Scandinavia Asia and Africa. In Japan it is extremely rare with a prevalence of 100000. Paget s disease is a localized disorder of bone remodeling. Excessive bone resorption and abnormal bone formation result in biomechanically weakened bone and predispose patients to fracture. Delayed union and non-union of fractures have been reported in patients with Paget s disease. Therefore open reduction and internal fixation of fractures has been recommended to prevent such complications. Here we report an unusual case of a 63-year-old Asian woman with delayed union of a femur fracture secondary to Paget s disease which was treated successfully by functional bracing. Introduction Paget s disease of the bone was first described by Sir James Paget in 1877. It is a well documented metabolic bone disorder in European countries and the United States with a reported incidence of 3-4 in the adult population 1-3 . Interestingly it is extremely rare in Africa and Asia and rarely occurs in Japanese individuals 3-6 . Although the etiology of Paget s disease remains unclear it is characterized by increased bone resorption bone formation and remodeling. The axial skeleton is frequently involved and the bones most commonly affected include the pelvis 70 femur 55 lumbar spine 53 skull 42 and tibia 32 7 . Increased bone turnover and remodeling leads to altered bone quality thickening enlargement and deformity. Paget

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