tailieunhanh - Báo cáo y học: " A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia. | Annals of General Hospital Psychiatry Primary research BioMed Central Open Access A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia Haya Ascher-Svanum Baojin Zhu Douglas Faries and Frank R Ernst Address Outcomes Research Eli Lilly and Company Indianapolis Indiana USA Email Haya Ascher-Svanum - haya@ BaojinZhu - Douglas Faries - Frank R Ernst - fre@ Corresponding author Published 02 June 2004 Received 16 December 2003 Accepted 02 June 2004 Annals of General Hospital Psychiatry 2004 3 11 This article is available from http content 3 l ll 2004 Ascher-Svanum et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background Decreasing hospital admissions is important for improving outcomes for people with schizophrenia and for reducing cost of hospitalization the largest expenditure in treating this persistent and severe mental illness. This prospective observational study compared olanzapine and risperidone on one-year psychiatric hospitalization rate duration and time to hospitalization in the treatment of patients with schizophrenia in usual care. Methods We examined data of patients newly initiated on olanzapine N 159 or risperidone N 112 who continued on the index antipsychotic for at least one year following initiation. Patients were participants in a 3-year prospective observational study of schizophrenia patients in the US. Outcome measures were percent of hospitalized patients total days hospitalized per patient and time to first hospitalization during the one-year post initiation. Analyses employed a generalized linear model with adjustments for demographic and clinical variables. A .

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