tailieunhanh - Báo cáo y học: " Off-label indications for atypical antipsychotics: A systematic review"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Off-label indications for atypical antipsychotics: A systematic review. | Annals of General Hospital Psychiatry BioMed Central Review Open Access Off-label indications for atypical antipsychotics A systematic review Konstantinos N Fountoulakis loannis Nimatoudis Apostolos lacovides and George Kaprinis Address 3rd Department of Psychiatry Aristotle University of Thessaloniki Greece Email Konstantinos N Fountoulakis - kfount@ IoannisNimatoudis - nimatoud@ Apostolos Iacovides - iacovid@ George Kaprinis - kaprinis@ Corresponding author Published 18 February 2004 Received 30 January 2004 Accepted 18 February 2004 Annals of General Hospital Psychiatry 2004 3 4 This article is available from http content 3 l 4 2004 Fountoulakis et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Introduction With the introduction of newer atypical antipsychotic agents a question emerged concerning their use as complementary pharmacotherapy or even as monotherapy in mental disorders other than psychosis. Material and method MEDLINE was searched with the combination of each one of the key words risperidone olanzapine and quetiapine with key words that refered to every DSM-IV diagnosis other than schizophrenia and other psychotic disorders bipolar disorder and dementia and memory disorders. All papers were scored on the basis of the JADAD index. Results The search returned 483 papers. The selection process restricted the sample to 59 papers concerning Risperidone 37 concerning Olanzapine and 4 concerning Quetiapine 100 in total . Ten papers 7 concerning Risperidone and 3 concerning Olanzapine had JADAD index above 2. Data suggest that further research would be of value concerning the use of risperidone in the treatment of refractory OCD Pervasive Developmental disorder stuttering and Tourette s .