tailieunhanh - Báo cáo y học: "Olanzapine-associated neuroleptic malignant syndrome: Is there an overlap with the serotonin syndrome"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Olanzapine-associated neuroleptic malignant syndrome: Is there an overlap with the serotonin syndrome? | Annals of General Hospital Psychiatry Primary research BioMed Central Open Access Olanzapine-associated neuroleptic malignant syndrome Is there an overlap with the serotonin syndrome Vassilis P Kontaxakis Beata J Havaki-kontaxaki Nikolaos G Christodoulou Konstantinos G Paplos and George N Christodoulou Address Department of Psychiatry University of Athens Eginition Hospital Athens Greece Email Vassilis P Kontaxakis - bkont@ Beata J Havaki-kontaxaki - bkont@ Nikolaos G Christodoulou - gnchrist@ Konstantinos G Paplos - bkont@ George N Christodoulou - gnchrist@ Corresponding author Published 29 October 2003 Received 27 November 2002 Accepted 29 October 2003 Annals of General Hospital Psychiatry 2003 2 10 This article is available from http content 2 1 10 2003 Kontaxakis et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background The neuroleptic malignant syndrome is a rare but serious condition mainly associated with antipsychotic medication. There are controversies as to whether classical forms of neuroleptic malignant syndrome can occur in patients given atypical antipsychotics. The serotonin syndrome is caused by drug-induced excess of intrasynaptic 5-hydroxytryptamine. The possible relationship between neuroleptic malignant syndrome and serotonin syndrome is at present in the focus of scientific interest. Methods This retrospective phenomenological study aims to examine the seventeen reported olanzapine - induced neuroleptic malignant syndrome cases under the light of possible overlap between neuroleptic malignant syndrome and serotonin syndrome clinical features. Results The serotonin syndrome clinical features most often reported in cases initially diagnosed as neuroleptic malignant .

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