tailieunhanh - Báo cáo y học: "Evaluating the Safety of Intranasal Steroids in the Treatment of Allergic Rhinitis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Evaluating the Safety of Intranasal Steroids in the Treatment of Allergic Rhinitis. | ORIGINAL ARTICLE Evaluating the Safety of Intranasal Steroids in the Treatment of Allergic Rhinitis Ketan Sheth MD MBA Given that intranasal corticosteroids INCs are widely considered first-line therapies for treatment of rhinitis it is important for the clinician to be comfortable with the side-effect profile and be able to discuss potential safety concerns regarding these therapies. Among the safety concerns with the use of INCs are the potential for growth suppression both short and long term the potential for hypothalamic-pituitary-adrenal axis suppression ocular safety and the use of INCs concomitantly with inhaled corticosteroids in asthma patients. As all clinicians are aware each patient can have individual responses to both efficacy and safety however the data reviewed suggest that the benefits outweigh the potential risks. Understanding the potential concerns and the data behind these concerns should give clinicians the information to be able to discuss this with patients and parents to incorporate appropriate therapy for those with allergic rhinitis. Key words allergic rhinitis intranasal corticosteroids safety treatment Allergic rhinitis AR affects almost 94 million Europeans 50 million Americans and 10 million Because it is so prevalent almost all primary care physicians will encounter this disease. Health Canada estimates that nonfood allergies are the most common chronic condition in Canadians 12 years of age and older. 1 In one study 42 of children were diagnosed with AR by the age of 6 years. The prevalence of AR has increased dramatically in the past 30 years and continues to increase. Children with one component of atopy AR asthma eczema have a threefold greater risk of developing a second In 1998 the Joint Task Force on Practice Parameters in Allergy Asthma and Immunology defined rhinitis as inflammation of the membrane lining the nose characterized by nasal congestion rhinorrhea sneezing itching of the nose and or .