tailieunhanh - Báo cáo y học: "Skin Test Reactivity to Indoor Allergens Correlates with Asthma Severity in Jeddah, Saudi Arabia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Skin Test Reactivity to Indoor Allergens Correlates with Asthma Severity in Jeddah, Saudi Arabia. | Original Article Skin Test Reactivity to Indoor Allergens Correlates with Asthma Severity in Jeddah Saudi Arabia Emad A. Koshak MD FRCPSC Abstract Background There is increased emphasis on the role of indoor allergens in asthma. Objective To examine the spectrum of skin test reactivity sensitization to indoor allergens and its correlation with asthma severity in Jeddah Saudi Arabia. Methods Asthmatic patients referred to the allergy clinic at King Abdulaziz University Hospital KAUH in Jeddah were studied. Measures of clinical severity were adopted from national and international asthma degree of sensitization was assessed by the wheal size positive 3 mm from standard skin-prick tests for the following common indoor inhalant allergens house dust mites Dermatophagoides pteronyssinus Dp and Dermatophagoides farinae Df cat and cockroach. Results Skin test results from 113 of 151 asthmatic patients were positive for one or more allergens. The patients ages ranged between 9 and 63 years mean 30 13 years and females constituted . The predominant asthma severity level was moderate persistent followed by mild persistent . The prevalences of sensitization to indoor allergens were as follows Dp 87 3-25 mm mean 7 mm Df 84 3-20 mm mean 7 mm cat 44 3-15 mm mean 6 mm and cockroach 33 3-12 mm mean 4 mm . Higher asthma severity levels were significantly correlated with the number of allergens with positive sensitization R p .001 and with the degree of sensitization to house dust mites Dp degrees of freedom df 16 p .001 and Df df 17 p .01 but not to cat df 10 p .24 or cockroach df 8 p .36 . Conclusions Immunoglobulin E-mediated skin test reactivity to indoor allergens particularly to house dust mites was common in asthmatic patients from Jeddah at KAUH. Increased sensitization was associated with higher levels of asthma severity which is compatible with the literature. This emphasizes the importance of identifying sensitization to relevant .